Learn More
OBJECTIVES We have reviewed our surgical experience to document intra- and postoperative mortality and morbidity in 656 patients with renal cell carcinoma who underwent nephrectomy through a transperitoneal anterior subcostal incision (TASI). MATERIALS AND METHODS From 1986 to 1997 we performed 656 nephrectomies for renal cell carcinoma using a TASI.(More)
OBJECTIVES To determine whether renal hybrid tumours (HT) appear as a specific clinical and radiological entity, as HT are characterized by the association of both oncocytes and chromophobe cells within the same tumour, and have been described in patients with oncocytosis and Birt-Hogg-Dube syndrome. PATIENTS AND METHODS We reviewed the medical charts of(More)
Disease-causing missense (and other in-frame) mutations can exert their deleterious effects at the cellular level through multiple mechanisms. A pathogenic mechanism involves the addition of a novel N-linked glycan. Up to 1.4% of known disease-causing missense mutations are predicted to give rise to gains-of-glycosylation. For some of these mutations, the(More)
PURPOSE Double-pigtail stent intolerance reduces patient's quality of life. By decreasing the amount of material within the bladder, it should be possible to attenuate stent's symptoms. We evaluated the tolerance of a new stent with a dedicated questionnaire. METHODS The major innovation of the pigtail suture stent (PSS) is in the replacement of the lower(More)
OBJECTIVE Double-pigtail stent intolerance reduces the quality of life of patients. By decreasing the amount of material within the bladder, it should be possible to attenuate the symptoms linked to the stent. We evaluated the tolerance of a new stent with a dedicated questionnaire. PATIENTS ET METHODS The major innovation of the pigtail suture stent (PSS(More)
We present the case of a patient with suspected genitourinary tuberculosis in whom confirmation by direct smear examination was negative. Detection of mycobacterial DNA by use of the polymerase chain reaction (PCR) established the diagnosis, which was confirmed by culture 4 weeks later. Given its very high sensitivity and positivity, PCR may become the(More)
BACKGROUND Fabry's disease (FD) is an inborn error of glycosphingolipid catabolism with progressive systemic deposition of globotriaosylceramide thereby leading to renal and cardiac failure. Current therapy involves symptomatic medical management, dialysis, enzyme replacement therapy, kidney transplantation (KTx), and more recently gene therapy. Case(More)
PURPOSE We describe a technical artifice facilitating nephron sparing surgery for renal cell carcinoma without clamping the renal pedicle. MATERIALS AND METHODS Selective renal parenchymal clamping was performed using a large curved DeBakey aortic clamp placed around and sufficiently far from the tumor. The lesion was resected with a surrounding margin of(More)
OBJECTIVES To describe and analyse the proposed therapeutic modalities to treat a series of patients suffering from Fournier's gangrene involving the entire scrotum. MATERIAL AND METHODS Four patients with macroscopically identical lesions of Fournier's gangrene involving the entire scrotum were managed by wide surgical debridement, diversion colostomy,(More)
Dear Editor: The ureteral stents are defined as devices that are inserted inside obstructive ureters to maintain patency. Ureteral obstruction caused by extrinsic compression is a challenge in the management of malignant diseases. 1,2 First, adequate stent placement across an obstructed ureter does not necessarily guarantee urine patency. 1 Moreover, the(More)