Benny S Kim
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PEN-2 and APH-1 Coordinately Regulate Proteolytic Processing of Presenilin 1*
Presenilin (PS, PS1/PS2) complexes are known to be responsible for the intramembranous γ-secretase cleavage of the β-amyloid precursor protein and signaling receptor Notch. PS holoprotein undergoes… Expand
Presenilin-1 Regulates Intracellular Trafficking and Cell Surface Delivery of β-Amyloid Precursor Protein*
- D. Cai, J. Y. Leem, +10 authors H. Xu
- Biology, Medicine
- The Journal of Biological Chemistry
- 31 January 2003
Presenilins (PS1/PS2) play a critical role in proteolysis of β-amyloid precursor protein (βAPP) to generate β-amyloid, a peptide important in the pathogenesis of Alzheimer's disease. Nevertheless,… Expand
Cationic colloidal gold staining of acidic glycoconjugates in mouse Paneth cells.
- Y. B. Ge, D. Yang, +4 authors F. Murata
- Chemistry, Medicine
- Archives of histology and cytology
- 1 June 1997
The acidic glycoconjugates of mouse ileum Paneth cells were examined with the aid of light and electron microscopy, using cationic colloidal gold (CCG) as a probe. Specimens of mouse ilea were fixed… Expand