Benjamin W. Caldwell

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We developed an integrated chip for real-time amplification and detection of nucleic acid using pH-sensing complementary metal-oxide semiconductor (CMOS) technology. Here we show an amplification-coupled detection method for directly measuring released hydrogen ions during nucleotide incorporation rather than relying on indirect measurements such as(More)
We have designed a skills matrix to be used for developing and assessing undergraduate biochemistry and molecular biology laboratory curricula. We prepared the skills matrix for the Project Kaleidoscope Summer Institute workshop in Snowbird, Utah (July 2001) to help current and developing undergraduate biochemistry and molecular biology program designers to(More)
In this paper, two approaches for computing the topological information content of function models in mechanical engineering design are developed and compared. Previously a metric for computing information content of functions and flows within function models was proposed. Here this metric is adapted to compute the information contained in the resulting(More)
Chiradeep Sen Graduate Student Benjamin W. Caldwell Graduate Student Joshua D. Summers 1 Associate Professor Gregory M. Mocko Assistant Professor Department of Mechanical Engineering, Clemson University, Clemson SC 29634-0921 Abstract A metric for computing information content of(More)
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