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  • Stephen D Bell, Catherine H. Botting, Benjamin N Wardleworth, Stephen P. Jackson, Malcolm F. White
  • Biology, Medicine
  • Science
  • 2002 (First Publication: 5 April 2002)
  • The conserved Sir2 family of proteins has protein deacetylase activity that is dependent on NAD (the oxidized form of nicotinamide adenine dinucleotide). Although histones are one likely target forContinue Reading
  • Benjamin N Wardleworth, Mamuka Kvaratskhelia, Malcolm F. White
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2000 (First Publication: 4 August 2000)
  • The Holliday junction-resolving enzyme Cce1 is a magnesium-dependent endonuclease, responsible for the resolution of recombining mitochondrial DNA molecules in Saccharomyces cerevisiae. We haveContinue Reading
  • Mamuka Kvaratskhelia, Benjamin N Wardleworth, Charles S. Bond, Jonathan M Fogg, David Lilley, Malcolm F. White
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2002 (First Publication: 25 January 2002)
  • The Holliday junction-resolving enzyme Hjc is conserved in the archaea and probably plays a role analogous to that of Escherichia coli RuvC in the pathway of homologous recombination. HjcContinue Reading
  • Benjamin N Wardleworth, Robyn J. Russell, Malcolm F. White, Garry L. Taylor
  • Biology, Medicine
  • Acta crystallographica. Section D, Biological…
  • 2001 (First Publication: 1 December 2001)
  • Crystals of Sso10b from the hyperthermophilic archaeon Sulfolobus solfataricus have been grown that diffract to 2.6 A resolution. The protein is a highly abundant non-specific double-strandedContinue Reading