Benjamin Kersten

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A wide-bore capillary gas chromatographic method has been developed to study the drug matrix effect on the determination of residual solvents in bulk pharmaceuticals. A selective method is achieved on a Restek wide-bore (0.53-mm i.d. x 30 m) open-tubular fused-silica column coated with a 5-micron film of 95% dimethyl-5% diphenyl polysiloxane protected by a(More)
We propose in this paper an iterative method composed of three steps to derive architecture alternatives from quality requirements using a catalogue of patterns and styles. The solution candidates are chosen by answering a set of questions which reflects the requirements. We instantiate then the solution candidates using a UMLbased enhancement of the(More)
An ion-pairing high-performance liquid chromatographic method has been developed for the determination of 5-aminosalicylic acid (5-ASA) bulk chemical in the presence of thirteen potential synthetic process impurities. In addition, the method is suitable for the determination of the in process intermediate, 5-nitrosalicylic acid. A selective method was(More)
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