Benjamin K S Chan

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A literature scan of the topic is done periodically The purpose of this report is to make available information regarding the comparative effectiveness and safety profiles of different drugs within pharmaceutical classes. Reports are not usage guidelines, nor should they be read as an endorsement of, or recommendation for, any particular drug, use or(More)
Females may be attracted to males genetically resistant to infectious diseases, and one potential mechanism for this mating bias is that such males may be better able to maintain high testosterone. To test these two hypotheses, we collected scent-marks from male house mice (Mus domesticus) genetically resistant and susceptible to Salmonella due to a single(More)
Deep sequencing allows for a rapid, accurate characterization of microbial DNA and RNA sequences in many types of samples. Deep sequencing (also called next generation sequencing or NGS) is being developed to assist with the diagnosis of a wide variety of infectious diseases. In this study, seven frozen brain samples from deceased subjects with recent(More)
Increasing prevalence and severity of multi-drug-resistant (MDR) bacterial infections has necessitated novel antibacterial strategies. Ideally, new approaches would target bacterial pathogens while exerting selection for reduced pathogenesis when these bacteria inevitably evolve resistance to therapeutic intervention. As an example of such a management(More)
With the growing global antimicrobial resistance crisis, there is a critical need for alternatives to conventional antibiotics, especially in developing countries. Virulent bacteriophages (phages) represent a viable antibacterial technology that could be particularly beneficial, since phages are active against antimicrobial-resistant bacteria, easy to(More)
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