Benjamin Fell

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IMPORTANCE OF THE FIELD Cellular replacement therapies in vascular and urogenital organ disorders require an abundant source of smooth muscle cells. A promising approach would be the directed myogenic differentiation (characterized by the expression of alpha-smooth muscle actin (alpha-SMA)) into a sufficient amount of smooth muscle cells through easily(More)
Daily treatment of female rats with medroxyprogesterone acetate in aqueous suspension resulted in adrenocortical atrophy. The doses given were those used for oestrus synchronisation. Intramuscular injections of 2-0 mg medroxyprogesterone acetate were used to investigate the atrophic process. Adrenocortical involution was associated with extensive single(More)
1. The mucosal and serosal surface dimensions of the rat duodenum, jejunum and ileum were obtained by measurement of photographs of histological sections. The surface areas were calculated from these data.2. Measurements were made on the intestines from virgin rats and from rats on the sixteenth day of lactation. The mucosal area/unit length of serosa was(More)
Copper deficiency had a differential effect between tissues in the rat pancreas. There was marked loss and atrophy of acinar cells, in which both hypertrophied and degenerating mitochondria were present. Cytochrome oxidase activity in acini was greatly depleted while monoamine oxidase activity was enhanced. Atrophy of acinar cells was accompanied by(More)