Benjamin Daniels

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BACKGROUND The greatest genetic risk factor for late-onset Alzheimer's disease (AD) is the ϵ4 allele of Apolipoprotein E (ApoE). ApoE regulates secretion of the potent neuroprotective signaling lipid Sphingosine 1-phosphate (S1P). S1P is derived by phosphorylation of sphingosine, catalysed by sphingosine kinases 1 and 2 (SphK1 and 2), and SphK1 positively(More)
  • K Hammond-Kosack, J D G Jones, In, Sandrock, D Vanetten, H D Purification +17 others
  • 2002
key area of interest will be establishing whether other pathogens, and possibly also symbionts, use similar mechanisms to colonize their plant hosts. A Methods Fungal strains and biochemical procedures S. lycopersici strains, culture conditions, genomic DNA extraction methods, tomatinase assays and tomatinase purification procedures have been described(More)
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