Benjamin Brinkhoff

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In the circle absorber system, a decrease in fresh gas flow means a higher degree of rebreathing, and, consequently, a higher temperature and humidity within the system. With our present hygienic routines, the circle system tubings are changed and decontaminated once daily. Thus, the same circle system is used for several patients each day. In order to(More)
The extent of staphylococcal colonisation and neonatal pyoderma was studied in 5 220 infants in two large Swedish hospitals in 1979-1982. A method for routine cord care with 4% chlorhexidine detergent solution was evaluated in one hospital. Nursery colonisation with Staph. aureus and streptococci decreased significantly. The method proved to be clinically(More)
The incidence and types of staphylococcal purulent lesions were prospectively studied among 3602 newborn infants. During an epidemic of post-discharge pyoderma, 87 per cent of all Staphylococcus aureus isolates from lesions could be traced to the nursery. The risk of post-discharge disease was related to the degree of staphylococcal skin colonization in the(More)
Immunotherapy of solid tumors is often hampered by the low frequency of tumor-specific T cells elicited by current vaccination strategies. Here, we describe a prime-boost vaccination protocol based on the administration of antigen conjugated to poly-lactic-co-glycolic acid (PLGA) microspheres followed by booster vaccination with Listeria monocytogenes(More)
A total of 533 throat and nasopharyngeal cultures were obtained from 328 staff who nursed cases of diphtheria and carriers of Corynebacterium diphtheriae; none yielded C. diphtheriae. Only one out of 189 environmental samples relating to 22 patients and carriers was positive. In addition, one carrier with chronic skin disease was found to have widespread(More)
The influence of aldosterone in vivo on cytochromes in rat kidney mitochondria is studied, comparing rats in normal state, adrenalectomized state, and adrenalectomized rats 2 hours after administration of adlosterone (7.5 μg per 100 g rat as single dose plus infusion of 0.125 μg per hour and 100 g rat). No significant changes between these states are(More)
To avoid elimination by the immune system, malignant cells establish a number of immunosuppressive mechanisms that inhibit cancer-specific immune responses. Owing to such a tumor antigen-specific immunosuppression, current anticancer vaccines induce immune responses that generally remain below the limit of detection. Ideally, vaccination should allow for(More)
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