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  • Steve Alas, Benjamin Bonavida
  • Medicine
  • Cancer research
  • 2001 (First Publication: 1 July 2001)
  • Development of the chimeric mouse antihuman CD20 antibody, Rituximab, presented a notable advance in the treatment of patients with non-Hodgkin's lymphoma (NHL). Its use allowed the specificContinue Reading
  • Golaun Odabaei, Devasis Chatterjee, Ali R. Jazirehi, Lee Goodglick, Kam Yeung, Benjamin Bonavida
  • Biology, Medicine
  • Advances in cancer research
  • 2004
  • The acquisition of resistance to conventional therapies such as radiation and chemotherapeutic drugs remains the major obstacle in the successful treatment of cancer patients. Tumor cells acquireContinue Reading
  • Ali R. Jazirehi, Mario I. Vega, Devasis Chatterjee, Lee Goodglick, Benjamin Bonavida
  • Medicine
  • Cancer Research
  • 2004 (First Publication: 1 October 2004)
  • Rituximab (Rituxan, IDEC-C2B8) has been shown to sensitize non-Hodgkin’s lymphoma (NHL) cell lines to chemotherapeutic drug-induced apoptosis. Rituximab treatment of Bcl-2–deficient Ramos cells andContinue Reading
  • Ali R. Jazirehi, Benjamin Bonavida
  • Medicine, Biology
  • Oncogene
  • 2005 (First Publication: 1 March 2005)
  • The clinical application of rituximab (chimeric mouse anti-human CD20 mAb, Rituxan, IDEC-C2B8), alone and/or combined with chemotherapy, has significantly ameliorated the treatment outcome ofContinue Reading
  • Pi-Chan Hu, Lance E. Hultin, +6 authors Janis V. Giorgi
  • Biology, Medicine
  • Journal of acquired immune deficiency syndromes…
  • 1995 (First Publication: 1 November 1995)
  • Natural killer (NK) cells were enumerated by three-color immunofluorescence in 255 uninfected and 399 human immunodeficiency virus-infected adults. Several dramatic alterations were observed. First,Continue Reading
  • Ali R. Jazirehi, Xiao-Hu Gan, Sven de Vos, Christos Emmanouilides, Benjamin Bonavida
  • Biology, Medicine
  • Molecular cancer therapeutics
  • 2003 (First Publication: 1 November 2003)
  • The anti-CD20 monoclonal antibody rituximab (Rituxan, IDEC-C2B8) has shown promising results in the clinical treatment of a subset of patients with low grade or follicular non-Hodgkin's lymphomaContinue Reading
  • Stavroula Baritaki, Alfred Chaston Chapman, Kam Yeung, Demetrios A. Spandidos, M Palladino, Benjamin Bonavida
  • Medicine, Biology
  • Oncogene
  • 2009 (First Publication: 1 October 2009)
  • Metastasis is associated with the loss of epithelial features and the acquisition of mesenchymal characteristics and invasive properties by tumor cells, a process known as epithelial to mesenchymalContinue Reading