Benedikt Sedlmaier

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The Gram-negative bacterium Helicobacter pylori is a causative agent of gastritis and peptic ulcer disease in humans. Strains producing the CagA antigen (cagA(+)) induce strong gastric inflammation and are strongly associated with gastric adenocarcinoma and MALT lymphoma. We show here that such strains translocate the bacterial protein CagA into gastric(More)
OBJECTIVE The aim of this study was to investigate the transtympanic ventilation time, the healing course of the tympanic membrane, the early and late complications, and the recurrence rate of otitis media with effusion (OME) within 6 months after CO2 laser myringotomy with the CO2 laser otoscope Otoscan. STUDY DESIGN Prospective clinical study. (More)
OBJECTIVES Long-term Eustachian tube dysfunction (ETD) predisposes to various secondary middle ear diseases. Most surgical and prosthetical interventions on the Eustachian tube itself have proven to be ineffective, whereas middle ear surgeries treat the sequelae of ETD without major influence on the underlying tubal pathology. The purpose of our study was(More)
OBJECTIVE Laser Eustachian tuboplasty (LETP) with ablation of the epipharyngeal orifice of the Eustachian tube (ET) shows good results in clinical observation. However, to this day, there are no reports evaluating the surgical procedure with valid test methods. The purpose of this study was to test the effect of minimally invasive LETP by means of a(More)
BACKGROUND The purpose of this study was to evaluate long-term outcomes of an outpatient-based diode laser inferior turbinate reduction (ITR) in therapy-refractory rhinitis medicamentosa (RM). METHODS In a prospective clinical investigation, 42 consecutive RM patients underwent videoendoscopic ITR with a diode laser after topical anesthetic preparation.(More)
A long-lasting dysfunction of the eustachian tube seems to be the etiologic origin for development of chronic otitis media (COM) with mesotympanic perforation, otitis media with effusion (OME), and chronic atelectasis of the middle ear. Surgical interventions in the middle ear generally treat the sequelae of the tube dysfunction but not the dysfunction(More)
BACKGROUND The clinical diagnosis of olfactory dysfunction of different etiologies has been standardized by the German Working Group of Olfactology and Gustology, but there is no agreement about the most suitable imaging modality for diagnosing this disorder. MATERIAL AND METHODS A total of 24 patients (13 women, 11 men; mean age 52 years) with different(More)
INTRODUCTION Impaired Eustachian tube function can limit one's fitness to dive. This study investigated the effect of minimally invasive laser Eustachian tuboplasty (laser tuboplasty) on tube function in divers and its long-term effect on their diving habits. METHODS In a prospective surgical trial in nine divers with tubal dysfunction, laser tuboplasty(More)
Hintergrund: Das wichtigste Prinzip in der Behandlung der sekretorischen Otitis media (SOM) ist die Belüftung der Pauke. Dies wird bei der CO2-Laserparazentese über eine selbstheilende Perforation erreicht, deren Durchmesser im Wesentlichen die Dauer der transtympanalen Belüftung bestimmt. Patienten, Methode: In dieser Untersuchung wurde bei 81 Kindern(More)
Die Belüftung der Pauke ist der wichtigste Faktor in der Behandlung der sekretorischen Otitis media (SOM). Die CO2-Laserparazentese ist ein modernes, schmerzarmes Verfahren zur artifiziellen Paukenbelüftung, das ohne Vollnarkose mit Oberflächenanästhesie auch bei Kindern durchgeführt werden kann. Die Belüftungsdauer des Mittelohrs wird im wesentlichen(More)