Benedetta Frida Baldi

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Schizophrenia is a multifactorial complex disease with a large impact on society. Many hypotheses have been proposed over the years to explain its causes, and genomics and functional genomic approaches may shed light on the reason behind these controversies and discrepancies. We give an overview of several approaches that have been used to identify the(More)
Well-designed videogames provide intuitive and engaging ways of understanding and interacting with highly complex systems. The aim of this study was to explore the use of videogames as a lens for the design of bioinformatics visualisation tools, with a particular focus on molecular graphics systems designed to explore 3D structures of proteins. We conducted(More)
We sought to explore how knowledge of videogames could inform the design of complex digital interfaces for bioinformatics visualization tools. Aquaria is an open-source web resource for visual exploration of protein structures. We present the results of a series of workshops conducted with participants who have expertise in videogame design and development.(More)
This dissertation is the result of my own work and includes nothing which is the outcome of work done in collaboration except where specifically indicated in the text. This thesis does not exceed the specified length limit of 60.000 words as defined by the Biology Degree Committee. This thesis has been typeset in 12pt font using Latex according to the(More)
Long Term Potentiation (LTP) is thought to be one of the main molecular mechanisms underlying the processes of memory and learning in the brain. One of the most studied mechanisms is the synaptic potentiation mediated by glutamate and its receptors resulting in conductance changes of the post-synaptic membrane. Brain-derived neurotrophic factor and its(More)
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