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The widespread distribution and relapsing nature of Plasmodium vivax infection present major challenges for the elimination of malaria. To characterize the genetic diversity of this parasite in individual infections and across the population, we performed deep genome sequencing of >200 clinical samples collected across the Asia-Pacific region and analyzed(More)
The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is the result of a soft selective sweep involving at least 20 independent kelch13 mutations. In a large global survey, we find that kelch13 mutations which cause resistance in Southeast Asia are present at low frequency in Africa. We show that African kelch13 mutations(More)
The frequent occurrence of aspergillosis caused by species other than Aspergillus fumigatus at Brooke Army Medical Center prompted the authors to study the prevalence of the different Aspergillus species at Brooke Army Medical Center and at two other hospitals in San Antonio, Texas. Two parameters were analyzed: (1) frequency of isolation from clinical(More)
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