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Hair follicles are spaced apart from one another at regular intervals through the skin. Although follicles are predominantly epidermal structures, classical tissue recombination experiments indicated that the underlying dermis defines their location during development. Although many molecules involved in hair follicle formation have been identified, the(More)
We examined the rates of infection and colonisation by methicillin-resistant Staphylococcus aureus (MRSA) between January 2003 and May 2004 in order to assess the impact of the introduction of an MRSA policy in October 2003, which required all admissions to be screened. Emergency admissions were treated prophylactically and elective beds ring-fenced. A(More)
RhoA is a small guanosine-5'-triphosphatase (GTPase) suggested to be essential for cytokinesis, stress fiber formation, and epithelial cell-cell contacts. In skin, loss of RhoA was suggested to underlie pemphigus skin blistering. To analyze RhoA function in vivo, we generated mice with a keratinocyte-restricted deletion of the RhoA gene. Despite a severe(More)
TO THE EDITOR Human and rodent LCE gene clusters are located on the epidermal differentiation complexes (EDC; 1q21 in human , 3F2.1 in mouse and 2q34 in rat) and encode multiple small genes with similarities, particularly over their N-terminal region, to small proline-rich proteins. Many LCE genes contain the glycine–serine–cysteine-rich motif typical of(More)
A mouse monoclonal antibody (MAb) recognizing alpha-smooth-muscle actin has been used to study smooth-muscle differentiation features in the stromal cells of desmoplastic reactions accompanying mammary tumors. We have studied, by the same immunohistochemical technique, a series of malignant and non-malignant human breast tissues. Cells composing the(More)
OBJECTIVE To examine the effects of communication skills training on physiotherapists' supportive behavior during clinical practice. DESIGN Randomized trial. SETTING Hospital outpatient physiotherapy clinics. PARTICIPANTS Physiotherapists (N=24) and patients (N=24) with chronic low back pain. INTERVENTIONS Two hospital clinics were randomly assigned(More)
PURPOSE Within supervised rehabilitation programs, Lent and Lopez (2002) proposed that clients and therapists develop a "tripartite" network of efficacy beliefs, comprising their confidence in their own ability, their confidence in the other person's ability, and their estimation of the other person's confidence in them. To date, researchers have yet to(More)
Actin isoform expression may change during development, and in certain physiological, experimental and pathological situations. It is accepted that during sarcomeric (skeletal and cardiac) muscle development, the alpha-skeletal and alpha-cardiac isoforms of actin accumulate rapidly at the onset of muscle fibre formation, while there is a rapid fall in the(More)
A 33-year-old woman presenting with secondary amenorrhea and galactorrhea was found to have a Sertoli cell tumor of the ovary. The neoplasm also had a sex cord tumor with annular tubules (SCTAT) component. Further investigations revealed that in many respects the patient was endocrinologically pregnant. She had markedly elevated serum estrogen and(More)
Although researchers have experimentally examined the mechanisms underlying pressure-induced forms of suboptimal performance, or "choking under pressure," there is a lack of research exploring the personal experience of this phenomenon. In an attempt to fill this void in the literature, this study explored experienced golfers' perceptions of the choking(More)