Ben H. Jansen

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This study deals with neurophysiologically based models simulating electrical brain activity (i.e., the electroencephalogram or EEG, and evoked potentials or EPs). A previously developed lumped-parameter model of a single cortical column was implemented using a more accurate computational procedure. Anatomically acceptable values for the various model(More)
OBJECTIVE We investigated the role of phase synchronization of the spontaneous electroencephalogram (EEG) in auditory evoked potential (EP) generation in a sample of healthy individuals. METHODS Auditory responses were obtained from 20 healthy subjects following a double stimulus paradigm, using two identical tone bursts (S1 and S2) separated by 0.5s.(More)
Sensory gating during preattentive phases of information processing has been extensively examined. Sensory gating processes that occur during subsequent phases of information processing have not been fully examined. The relationship between P50 sensory gating and schizophrenia symptoms remains underspecified and the clinical correlates of N100 and P200(More)
Evidence is presented that a neurophysiologically-inspired mathematical model, originally developed for the generation of spontaneous EEG (electroencephalogram) activity, can produce VEP (visual evoked potential)-like waveforms when pulse-like signals serve as input. It was found that the simulated VEP activity was mainly due to intracortical excitatory(More)
The relationship between the latencies and amplitudes of the N1 and P2 components of the averaged visual evoked potential (EP) and the phase of the alpha activity immediately preceding the time of the stimulus, has been investigated in 7 male subjects. Low intensity flashes, delivered randomly between 2 and 6 whole seconds, were used as the stimuli. The(More)
The relationship between the latencies and amplitudes of the N1 and P2 components of the visual evoked potential (VEP) and the psychophysiological state of the brain immediately preceding the time of the stimulus has been investigated in 7 male subjects. Power spectral measures in the delta, theta, alpha and beta bands of the 1 sec pre-stimulus EEG were(More)
Root-mean-square (RMS) amplitude derived from power spectral measures in the alpha band of the 1 s prestimulus EEG were related to the peak-to-peak amplitude of the N1 and P2 components (N1P2PP) of the visual evoked potential (VEP) in 7 male subjects. Stimuli were low intensity flashes delivered randomly between 2 and 6 whole seconds. Trials were rank(More)
OBJECTIVE We have shown previously [Clin Neurophysiol 2003;114:79] that phase reorganization of the ongoing electroencephalogram (EEG) plays an important role in the generation of auditory evoked potential (EP) components with a latency between 50 and 200 ms. In the present study, we investigate whether schizophrenia patients suffer from phase(More)
A threshold detector for single-trial P300 detection has been evaluated. The detector operates on the 0-4 Hz band, isolated from the raw electroencephalogram using low-pass filtering, wavelet transforms, or the piecewise prony method (PPM). A detection rate around 70% was found, irregardless of stimulus type, interstimulus interval (ISI), probability of(More)
A method is described to detect (subtle) changes in an EEG (electroencephalogram) by means of a Markovian modeling approach. This method, termed structural EEG analysis, treats the non-stationary EEG as a sequence of a finite number of short elementary patterns. Subtle changes in an EEG may be detected by studying the transition probabilities between the(More)