Learn More
Infectious and inflammatory diseases have repeatedly shown strong genetic associations within the major histocompatibility complex (MHC); however, the basis for these associations remains elusive. To define host genetic effects on the outcome of a chronic viral infection, we performed genome-wide association analysis in a multiethnic cohort of HIV-1(More)
Four widely used in vitro assays for genetic toxicity were evaluated for their ability to predict the carcinogenicity of selected chemicals in rodents. These assays were mutagenesis in Salmonella and mouse lymphoma cells and chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells. Seventy-three chemicals recently tested in(More)
Acknowledgements This research report is the result of two interconnected research projects, the EPSRC funded ARCC-Water (Adaptation and Resilience in a Changing Climate) project, and the ESRC/DEFRA/Scottish Government funded Sustainable Practices Research Group 'Patterns of Water' project. We would like to thank the following people and organisations for(More)