Benôit Marin

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Extranodal NK/T-cell lymphoma, nasal type, is a rare and highly aggressive disease with a grim prognosis. No therapeutic strategy is currently identified in relapsing patients. We report the results of a French prospective phase II trial of an L-asparaginase-containing regimen in 19 patients with relapsed or refractory disease treated in 13 centers. Eleven(More)
Victor Aboyans, MD, PhD, FAHA, Chair; Michael H. Criqui, MD, MPH, FAHA, Co-Chair; Pierre Abraham, MD, PhD; Matthew A. Allison, MD, MPH, FAHA; Mark A. Creager, MD, FAHA; Curt Diehm, MD, PhD; F. Gerry R. Fowkes, MBChB, PhD, FAHA; William R. Hiatt, MD, FAHA; Björn Jönsson, MD, PhD; Philippe Lacroix, MD; Benoı̂t Marin, MD; Mary M. McDermott, MD, FAHA; Lars(More)
OBJECTIVES The aims were to analyse changes in nutritional parameters from diagnosis of amyotrophic lateral sclerosis (ALS) to death and to assess their relationships with survival at the time of diagnosis and during follow-up. METHODS 92 ALS patients were included and clinically assessed every 3 months (ALS functional rating scale, manual muscular(More)
OBJECTIVE To determine whether rituximab 375 mg/m(2) was efficacious in patients with immunoglobulin M (IgM) anti-myelin-associated glycoprotein antibody demyelinating neuropathy (IgM anti-MAG demyelinating neuropathy). METHODS Fifty-four patients with IgM anti-MAG demyelinating neuropathy were enrolled in this randomized, double-blind, placebo-controlled(More)
Epilepsy is, above all tropical, moreover, very african in its frequency and gravity. Data on the prevalence of epilepsy shows it to be two or three times more prevalent in tropical zones than in industrialized countries in non tropical areas, however it is rare to find data on the incidence and prognosis of epilepsy in sub-Saharan Africa. It is difficult(More)
OBJECTIVE To study subsequent fertility of patients who underwent embolization of the uterine arteries to treat postpartum hemorrhage. DESIGN Retrospective cohort study between January 2000 and June 2006 with two patient groups: exposed and nonexposed to embolization for postpartum hemorrhage. SETTING Level 3 maternity unit. PATIENT(S) Fifty-three(More)
OBJECTIVE To assess the efficacy of a limited, tailored training program for noncardiologist residents without experience in ultrasound to reach competence in basic critical care echocardiography. DESIGN Prospective descriptive clinical study. SETTING Medical-surgical intensive care unit of a teaching hospital. PATIENTS 201 patients (125 men; age: 61(More)
OBJECTIVE To assess whether immunodeficiency is associated with the most frequent non-AIDS-defining causes of death in the era of combination antiretroviral therapy (cART). DESIGN Observational multicentre cohorts. METHODS Twenty-three cohorts of adults with estimated dates of human immunodeficiency virus (HIV) seroconversion were considered. Patients(More)
Our objective was to assess the incidence of amyotrophic lateral sclerosis (ALS), and its temporal variations, between 1997 and 2007. The study was based on data prospectively gathered by the referral ALS 'expert centre' of the Regional University Hospital of Limousin (710,792 inhabitants). Patients were included if they were diagnosed with ALS according to(More)
To review how the phenotype and outcome of amyotrophic lateral sclerosis (ALS) change with variations in population ancestral origin (PAO). Knowledge of how PAO modifies ALS phenotype may provide important insight into the risk factors and pathogenic mechanisms of the disease. We performed a systematic review and meta-analysis of the literature concerning(More)