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Kcnq1ot1 is a long noncoding ribonucleic acid (RNA; lncRNA) that participates in the regulation of genes within the Kcnq1 imprinting domain. Using a novel RNA-guided chromatin conformation capture method, we demonstrate that the 5' region of Kcnq1ot1 RNA orchestrates a long-range intrachromosomal loop between KvDMR1 and the Kcnq1 promoter that is required(More)
We evaluated earthquake research performance based on a bibliometric analysis of 84,051 documents published in journals and other outlets contained in the Scientific Citation Index (SCI) and Social Science Citation Index (SSCI) bibliographic databases for the period of 1900–2010. We summarized significant publication indicators in earthquake research,(More)
An effective bibliometric analysis based on the Science Citation Index-Expanded database was conducted to evaluate earth science sediment-related research from different perspectives from 1992 to 2011. The geographical influences of the authors were subsequently visualized. Sediment-related research experienced notable growth in the past two decades.(More)
Monoallelic expression of IGF2 is regulated by CCCTC binding factor (CTCF) binding to the imprinting control region (ICR) on the maternal allele, with subsequent formation of an intrachromosomal loop to the promoter region. The N-terminal domain of CTCF interacts with SUZ12, part of the polycomb repressive complex-2 (PRC2), to silence the maternal allele.(More)
Our analysis—as many other bibliometric studies—focused on aggregated and overall patterns in scientific development. It is our belief that, as long as the bibliometric samples are selected in a rational, representative, and consistent manner, the exact number of articles in a sample is not a significant concern. The 84,051 papers reported in the article(More)
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