Behrooz Nasseri

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The mechanical characteristics of non-ionic bilayer membranes composed of sorbitan monostearate, cholesterol and poly-24-oxyethylene cholesteryl were studied by measuring the modulus of surface elasticity (mu), a measure of membrane strength, as a function of cholesterol content and temperature. The modulus of surface elasticity increased slowly with(More)
Polyhedral non-ionic surfactant vesicles formed from mixtures of polyoxyethylene-5-cetyl ether (C(16)EO(5)) or polyoxethylene-5-stearyl ether (C(18)EO(5)) with poly-24-oxyethylene cholesteryl ether (Solulan C24) and low amounts of cholesterol, when extruded from microcapillaries under pressure fuse to form multi-lamellar tubules up to about 80 microm in(More)
Microparticles and nanoparticles used in drug delivery frequently depend on their movement in confined spaces such as cells. Liposomes containing small numbers of 1-µm diameter polystyrene particles were used to study the dynamics of their movement within the confined space of the liposome interior. The analysis of the trajectories of single and multiple(More)
Micromanipulation of the external bilayers of nonionic surfactant vesicles (niosomes) and liposomes allows the formation of tethers, which are fluid state lipid/surfactant lamellar nanotubes. The technique allows investigation of some of the factors affecting tether formation and vesicle-tether interactions. In this paper the movement of a vesicle along, or(More)
Polyhedral non-ionic surfactant vesicles (niosomes) undergo complex shape transitions as a result of mechanical stress. When extruded under pressure from capillaries with exit diameters smaller than the diameter of the vesicles, a series of novel structures comprising mostly of tubules, vesicles inside tubules and concentric structures can be formed. The(More)
Lipid nanotubes or "tethers" can be formed from liposomes or niosomes, pulled from the parent vesicles by micromanipulation. The tethers are cylindrical multibilayer tubes. Here, we describe the movement of these multilamellar walls, initiated by creating a surface tension gradient along the tether. The movement of lipid can give rise to a visible moving(More)
The malleability of soft matter such as vesicular systems, allows their mechanical manipulation into various interesting structures. Their inherent elastic membrane properties can be utilized in fabricating micro-scaled transport machineries. In this paper, we have described several features of research carried out in our laboratory. This includes the(More)
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