• Publications
  • Influence
4-Hydroxyphenylpyruvate Dioxygenase Inhibitors: From Chemical Biology to Agrochemicals.
TLDR
This review focuses on the chemical biology of HPPD, discovery of new potential inhibitors, and strategies for engineering transgenic crops resistant to current HPPD-inhibiting herbicides and raises some relevant gaps for future research directions. Expand
Hsp70/Hsp90 co‐chaperones are required for efficient Hsp104‐mediated elimination of the yeast [PSI+] prion but not for prion propagation
TLDR
It is shown that deletion of the STI1 and CPR7 genes leads to a significant reduction in the generation of [psi−] cells by Hsp104 overexpression, providing support for the hypothesis that [PSI+] elimination by HSp104 overeexpression is not simply a consequence of complete dissolution of the prion aggregates but rather is through a mechanism distinct from the remodelling activity of Hsp 104. Expand
CO2 Cycloaddition to Epoxides by using M‐DABCO Metal–Organic Frameworks and the Influence of the Synthetic Method on Catalytic Reactivity
TLDR
It was found that the synthesis procedure clearly influenced the crystal growth and thus the physicochemical properties, such as surface area, pore volume, and gas adsorption, which in turn affected the catalytic performance. Expand
Zeolitic imidazole framework-67 as an efficient heterogeneous catalyst for the conversion of CO2 to cyclic carbonates
Zeolitic imidazole framework (ZIF)-67 is an efficient heterogeneous catalyst for the cycloaddition of carbon dioxide to epoxides to afford cyclic carbonates. In this work, ZIF-67 was synthesized by aExpand
The assembly of succinate dehydrogenase: a key enzyme in bioenergetics
TLDR
This review is an overview of the SDH assembly factors and critical analysis of controversial issues around them and speculate it might be possible to design novel fungicides specifically targeting fungal assembly factors. Expand
Discovery of a butyrylcholinesterase-specific probe via a structure-based design strategy.
TLDR
The structure-based design and application of a fluorogenic molecular probe specific to butyrylcholinesterase (BChE-FP) is reported, which exhibits high specificity toward BChE compared to AChE, producing about 275-fold greater fluorescence enhancement upon the catalysis by B ChE. Expand
Molecular pathogenesis of tumorigenesis caused by succinate dehydrogenase defect.
TLDR
How defective SDH may lead to tumor development at the molecular level is discussed and how yeast, as a model system, has contributed to understanding the molecular pathogenesis of tumorigenesis resulting from defectiveSDH is described. Expand
Yeast Model of Amyloid-β and Tau Aggregation in Alzheimer's Disease.
TLDR
Yeast is eukaryotes, just like us, and are amenable to effects and expression of Aβ and tau and appear able to 'report' with considerable relevance on the effects of these biomolecules. Expand
Genetic, epigenetic and biochemical regulation of succinate dehydrogenase function
TLDR
The molecular pathways which regulate SDH function are discussed and extra roles played by SDH in specific cell types are described and described to support the development of therapeutic approaches against the diseases. Expand
Yeast-based assays for detecting protein-protein/drug interactions and their inhibitors.
TLDR
Different yeast-based assays for identification of various protein-protein/drug/inhibitor interactions and their specific applications, advantages, shortcomings, and improvements are described. Expand
...
1
2
...