Behnood Gholami

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Pain assessment in patients who are unable to verbally communicate with medical staff is a challenging problem in patient critical care. The fundamental limitations in sedation and pain assessment in the intensive care unit (ICU) stem from subjective assessment criteria, rather than quantifiable, measurable data for ICU sedation and analgesia. This often(More)
Current clinical practice involves classification of biopsied or resected tumor tissue based on a histopathological evaluation by a neuropathologist. In this paper, we propose a method for computer-aided histopathological evaluation using mass spectrometry imaging. Specifically, mass spectrometry imaging can be used to acquire the chemical composition of a(More)
Pain assessment in patients who are unable to verbally communicate is a challenging problem. The fundamental limitations in pain assessment in neonates stem from subjective assessment criteria, rather than quantifiable and measurable data. This often results in poor quality and inconsistent treatment of patient pain management. Recent advancements in(More)
Atrial fibrillation, a cardiac arrhythmia characterized by unsynchronized electrical activity in the atrial chambers of the heart, is a rapidly growing problem in modern societies. One treatment, referred to as catheter ablation, targets specific parts of the left atrium for radio frequency ablation using an intracardiac catheter. Magnetic resonance imaging(More)
Glioma histologies are the primary factor in prognostic estimates and are used in determining the proper course of treatment. Furthermore, due to the sensitivity of cranial environments, real-time tumor-cell classification and boundary detection can aid in the precision and completeness of tumor resection. A recent improvement to mass spectrometry known as(More)
Critical care patients undergoing surgery require drug administration to regulate physiological variables such as blood pressure, cardiac output, heart rate, and degree of consciousness. The rate of infusion of each administered drug is critical, requiring constant monitoring and frequent adjustments. Patients in the intensive care unit who require(More)
Patients in the intensive care unit who require mechanical ventilation due to acute respiratory failure also frequently require the administration of sedative agents. The need for sedation arises both from patient anxiety due to the loss of personal control and the unfamiliar and intrusive environment of the intensive care unit, and also due to pain or(More)
1Department of Neurosurgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA 2Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA 3School of Aerospace Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA 4Department of Anesthesiology, Northeast Georgia Medical Center, Gainesville, GA 30503, USA(More)
In this paper, we present an analysis and synthesis framework for guaranteeing that the phase of a single-input, single-output closed-loop transfer function is contained in the interval [−α, α] for a given α > 0 at all frequencies. Specifically, we first derive a sufficient condition involving a frequency domain inequality for guaranteeing a given phase(More)
Gait analysis of patients with neurological disorders, including multiple sclerosis (MS), is important for rehabilitation and treatment. The Mircrosoft Kinect sensor, which was developed for motion recognition in gaming applications, is an ideal candidate for an inexpensive system providing the capability for human gait analysis. In this research, we(More)