Begoña Calvo

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We present here a three-dimensional FE model of the healthy human knee that included the main structures of the joint: bones, all the relevant ligaments and patellar tendon, menisci and articular cartilages. Bones were considered to be rigid, articular cartilage and menisci linearly elastic, isotropic and homogeneous and ligaments hyperelastic and(More)
The aim of refractive corneal surgery is to modify the curvature of the cornea to improve its dioptric properties. With that goal, the surgeon has to define the appropriate values of the surgical parameters in order to get the best clinical results, i.e., laser and geometric parameters such as depth and location of the incision, for each specific patient. A(More)
BACKGROUND Although heavyweight (HW) or lightweight (LW) polypropylene (PP) meshes are widely used for hernia repair, other alternatives have recently appeared. They have the same large-pore structure yet are composed of polytetrafluoroethylene (PTFE). This study compares the long-term (3 and 6 months) behavior of meshes of different pore size (HW compared(More)
Killer cell immunoglobulin-like receptors (KIR) form a group of regulatory molecules that specifically recognize HLA class I molecules, modulating cytolytic activity of natural killer cells. The number of KIR genes can vary between individuals, significant allelic variations have been described, and KIR genes are organized in a complex and heterogeneous(More)
BACKGROUND The anterior cruciate is the most frequent knee ligament to be totally disrupted. Surgical reconstruction of the anterior cruciate ligament is a common practice to treat the disability or chronical instability of knees due to anterior cruciate ligament insufficiency. Some of the factors that influence the success or failure of the anterior(More)
Total meniscectomies are commonly thought to cause progressive degenerative arthrosis pathology in articular cartilage in a period of a few years because of alteration of the biomechanical environment including increased joint instability. This concern has lead to a preference for partial meniscectomies, although lateral partial meniscectomies sometimes(More)
The major susceptibility locus for type 1 diabetes mellitus (T1D) maps to the human lymphocyte antigen (HLA) class II region in the major histocompatibility complex on chromosome 6p21. In southern European populations, like the Basques, the greatest risk to T1D is associated with DR3 homo- and heterozygosity and is comparable to that of DR3/DR4, the highest(More)
In order to simulate the corneal incisions used to correct astigmatism, a three-dimensional finite element model was generated from a simplified geometry of the anterior half of the ocular globe. A hyperelastic constitutive behavior was assumed for cornea, limbus and sclera, which are collagenous materials with a fiber structure. Due to the preferred(More)
We propose an online solution to non-rigid structure from motion that performs camera pose and 3D shape estimation of highly deformable surfaces on a frame-by-frame basis. Our method models non-rigid deformations as a linear combination of some mode shapes obtained using modal analysis from continuum mechanics. The shape is first discretized into linear(More)
The goal of this study was to characterize the passive elastic behaviour of muscle and tendon tissues of rat tibialis anterior. For that purpose, tissue samples from 3 month old female Wistar rats (210+/-11g) were mechanically tested in vitro. Moreover, an in vivo device was developed to measure the muscle-tendon unit response to increasing load. Mechanical(More)