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Quinones permeate our biotic environment, contributing to both homeostasis and cytotoxicity. All quinones generate reactive oxygen species through redox cycling, while partially substituted quinones… Continue Reading
Human parathyroid hormone-1 receptor (hPTHR1) belongs to class II of the G protein-coupled receptor (GPCR) family, whose members all contain a seven-transmembrane helix domain. The receptor regulates… Continue Reading
The dramatic advancements in the field of vaccinology has led to the formulation of chemically well defined vaccines composed of synthetic peptides and recombinant proteins derived from the… Continue Reading
Men who have sex with men (MSM) are at increased risk for HIV infection in India, particularly those who engage in transactional sex with other men (i.e., male sex workers; MSW). Despite the need,… Continue Reading
Identification and quantitative estimation of quinone metabolites of gamma-tocopherol (gamma-T) and its derivative gamma-carboxyethyl hydroxychroman (gamma-CEHC) are complicated by their functions as… Continue Reading
Abstract In the present study, synthetic peptides (EENVEHDA)2 [(oc)2] and (DDEHVEEPTVA)2 [(un)2] of ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum were linked with palmitic… Continue Reading
Identification and quantitative estimation of quinone metabolites of γ-tocopherol (γ-T) and its derivative γ-carboxyethyl hydroxychroman (γ-CEHC) are complicated by their functions as arylating… Continue Reading
Novel dithioic acid derivatives have been synthesized from 3 different natural acids having marked anti-inflammatory activities including ferulic acid, cinnamic acid and salicylic acid. The… Continue Reading
Synthesis of a highly functionalised triquinane 4 from 2-hydroxy-3-methoxy-6-methylbenzyl alcohol is reported.