Bee Leng Lee

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This phase II study was designed to determine the objective response rate and 6-month progression free survival of adult patients with recurrent supratentorial anaplastic glioma when treated with the immune modulator, polyinosinic-polycytidylic acid stabilized with polylysine and carboxymethylcellulose (poly-ICLC). This was an open-labeled, single arm phase(More)
We have developed and validated catheterization protocols in mice that allow for simultaneous infusion and sampling. A sampling catheter was inserted in the lateral vein of the tail, while the animals were infused either intravenously or intragastrically through a second catheter placed in the contralateral lateral vein or via an intragastric catheter,(More)
Due to the impact of time-dependent unit unavailability, the testing strategies (e.g., simultaneous or staggered testing) have significant effect on the system unavailability for complex standby systems. Several testing strategies have been studied to minimize average system unavailability for certain systems. For example, uniformly staggered testing has(More)
OBJECTIVES A recent systematic review confirmed the usefulness of fecal calprotectin (FC) in distinguishing organic (inflammatory bowel disease (IBD)) from non-organic gastrointestinal disease (irritable bowel syndrome (IBS)). FC levels <50 μg/g have a negative predictive value >92% to exclude organic gastrointestinal (GI) disease. Levels >250 μg/g(More)
Much research has been done on random polynomials. Topics of past investigation include estimating the number of zeros, finding the roots (and associated distributions), and confidence intervals for the roots of random polynomials. Research regarding the extrema of random polynomials and their associated confidence intervals is lacking. Fairley performed a(More)
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