Beatriz P Runkle

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Summary: Seventeen piglets were infected with a continuous intravenous infusion of live group B β-hemolytic streptococci (GBS). Hemodynamic changes were recorded, and blood samples were drawn for measurement of thromboxane B2 (TxB2) (stable metabolite of thromboxane A2) and 6-keto-PGF1α (stable metabolite of prostacyclin). Control animals (n =9) received(More)
The short-term effects of muscle relaxation with pancuronium bromide on arterial blood gas values, heart rate, and arterial blood pressure were studied in 49 neonates receiving mechanical ventilation. After pancuronium administration, mean PaO2 increased from 61.9 +/- 30.0 to 80.9 +/- 52.8 mm Hg (P = 0.006), mean PaCO2 decreased from 40.1 +/- 13.0 to 37.5(More)
We describe a two-year-old girl with 22q13 deletion syndrome (MIM # 606232), 46, XX, de l (22) (q13.31). ish del (22) (q13.31) (TUPLE 1+,ARSA-). The patient has hypotonia, normal growth, severe expressive language delay, mild mental retardation, and minor dysmorphic facial features. In addition, she had central diabetes insipidus that was diagnosed at age(More)
To evaluate the cardiovascular effects of FPL57231 on the early phase of GBS, paralyzed, mechanically ventilated piglets received a continuous IV infusion of GBS (4×108 org/kg/min) while aortic (AoP) and pulmonary artery pressures (Ppa) were measured q 15 min ('). Cardiac output (CO) was measured by thermodilution. Control animals (C) (n=3) (X+SD;wt,(More)
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