Beatrice J. Edwards

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BACKGROUND Falls leading to disability are common occurrences with advancing age. Stepping is a natural protective option for maintaining balance and preventing falls. There are directionally dependent challenges for protective stepping associated with falls among older individuals. The aim of this study was to determine the stepping response patterns(More)
Falls following a meal occur commonly in older persons. These falls have been related to a decrease in postprandial blood pressure due to carbohydrates in the meal. The mechanism by which this occurs is not known. In this study, we examined the possible role of a vasodilatory peptide, calcitonin gene-related peptide (CGRP), which is released following(More)
OBJECTIVE To study the effect of an incident wrist fracture on functional status in women enrolled in the Study of Osteoporotic Fractures. DESIGN Prospective cohort study. SETTING Baltimore, Minneapolis, Portland, and the Monongahela valley in Pennsylvania, USA PARTICIPANTS: 6107 women aged 65 years and older without previous wrist or hip fracture(More)
BACKGROUND In light of the uncertainty surrounding the incidence of bisphosphonate-associated osteonecrosis of the jaw (BON) and concomitant risk factors, dentists have questioned how to manage the care of patients receiving oral bisphosphonate therapy. Expert panelists were selected by the American Dental Association Council on Scientific Affairs on the(More)
This study was conducted to assess the occurrence of fractures in solid-organ transplant recipients. Methods. Medical record review and surveys were performed. Patients received less than 6 months of glucocorticoids. Results. Of 351 transplant patients, 175 patients provided fracture information, with 48 (27.4%) having fractured since transplant (2-6(More)
OBJECTIVE To examine whether the effect of postmenopausal hormone therapy (HT) on brain volumes in women aged 65-79 years differs depending on type 2 diabetes status during postintervention follow-up of a randomized controlled clinical trial. METHODS The Women's Health Initiative randomized clinical trials assigned women to HT (0.625 mg/day conjugated(More)
Objective To study the effect of an incident wrist fracture on functional status in women enrolled in the Study of Osteoporotic Fractures. Design Prospective cohort study. Participants 6107 women aged 65 years and older without previous wrist or hip fracture recruited from the community between September 1986 and October 1988. Main outcome measure(More)
Amylin (islet amyloid polypeptide) is a recently identified pancreatic peptide. It has been shown to affect glucose metabolism both in vitro and in vivo. A cross sectional analysis of the effects of age on amylin secretion following a 75 g glucose tolerance test in a young (20-40 years), middle aged (41-60 years) and older (61-90 years) group was performed.(More)
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