Bashar Behnam

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In the course of their biological function, peptide hormones must be transferred from an aqueous phase to the lipid-rich environment of their membrane-bound receptor proteins. We have investigated the possible influence of phospholipids in this process, using 360-MHz 1H and 90-MHz 13C NMR spectroscopy to examine the association of the opioid peptides [Met]-(More)
Transfer of an aqueous-soluble peptide hormone or neurotransmitter such as [Met]- or [Leu]enkephalin (Tyr1-Gly2-Gly3-Phe4-Met5(Leu5)), to the lipid-rich environment of its membrane-embedded receptor protein may convert the peptide into a ("bioactive") conformation required for eliciting biological activity. We have examined by high-resolution nuclear(More)
(2013). "Resistance factors for ductile FRP-reinforced concrete flexural members. 3 4 ABSTRACT 5 To prevent damage caused by corroding reinforcement, fiber reinforced polymer (FRP) 6 reinforcing bars have been used in place of steel in a relatively small but increasing number of 7 structures in the civil infrastructure. A concern with the use of traditional(More)
Steel-reinforced concrete structural components are often associated with significant maintenance costs as a result of reinforcement corrosion. To mitigate this problem, fiberreinforced polymer (FRP) bars have been used in place of traditional steel reinforcement for some applications. The non-ductile response of typical FRP bars is a concern, however. To(More)
In recent years, ductile hybrid FRP (DHFRP) bars have been developed for use as tensile reinforcement. However, initial material costs regain high, and it is difficult to simultaneously meet strength, stiffness, ductility, and reliability demands. In this study, a reliability-based design optimization (RBDO) is conducted to determine minimum cost DHFRP bar(More)
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