Basak Duman

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We report the development of a method for diagnosis of heterozygous deletions or duplications based on measurement of gene copy number. The method involves amplifications of a test locus with unknown copy number and a reference locus with known copy number using real-time PCR. Progress of the PCR reactions is monitored using fluorigenic probes and a(More)
Author Affiliations: Departments of Clinical Pharmacology (N.U., P.V., S.W.L., M.G., M.D., R.P.E.D., H.B., R.H.H.) and Pathology and Medical Biology (G.M.M., H.G.), University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands and Department of Medical Pharmacology, Faculty of Medicine, University of Ankara, Ankara, Turkey (B.D.,(More)
Fermentation and hydrothermal methods were tested to reduce the phytic acid (PA) content of oat bran, and the effects of these methods on the dietary fiber (DF) and total phenolic (TP) contents as well as the antioxidant activity (AA) were also investigated. Fermentation with 6% yeast and for 6 h resulted in 88.2% reduction in PA content, while it only(More)
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