Bart Spaetgens

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OBJECTIVE Gout has been associated with a large number of co-morbidities. As yet, no co-morbidity measure has been validated for use in clinical studies in gout. This study aims to evaluate the content and construct validity of the Rheumatic Diseases Comorbidity Index (RDCI) and a gout-specifically modified RDCI (mRDCI) in patients with gout. METHODS In a(More)
OBJECTIVES The Gout Assessment Questionnaire 2.0 (GAQ2.0) is a disease-specific patient-reported outcome measure for gout that distinguishes five different subscales and comprises overall 31 questions. The aims of this study were to translate the GAQ2.0 into Dutch and to test clinimetric properties. METHODS Recommendations for translation and(More)
OBJECTIVE To estimate costs of illness in a cross-sectional cohort of patients with gout attending an outpatient rheumatology clinic, and to evaluate which factors contribute to higher costs. METHODS Altogether, 126 patients with gout were clinically assessed. They completed a series of questionnaires. Health resource use was collected using a self-report(More)
OBJECTIVE To compare limitations in health between Dutch patients with gout and the general population and to determine factors influencing societal and patient values for health as assessed with different utility approaches. METHODS A cross-sectional study was done among 110 patients with gout under the care of a rheumatologist, with patients completing(More)
To investigate the risk of various types of infections (pneumonia and urinary tract infection (UTI)), and infection-related mortality in patients with gout compared with population-based controls. A retrospective cohort study was conducted using data from the UK Clinical Practice Research Datalink (CPRD). All patients with a first diagnosis of gout and aged(More)
An increase of 6% in the risk of vascular disease among men with gout (adj. HR 1.06 95% CI 1.01 to 1.12) and of 25% among women with gout (adj. HR 1.25 95%CI 1.15 to 1.35) was reported when analysing data of the world’s largest primary care database, the UK Clinical Practice Research Datalink. However, the statistical analyses are likely to suffer from(More)
OBJECTIVE To investigate construct validity of radiographic damage of the feet in gout. METHODS Radiographs of the feet were scored using the Sharp/van der Heijde method. Factors associated with damage were investigated by a negative binomial model, and contribution of damage to health by linear regressions. RESULTS Age, disease duration, serum uric(More)
The objective of the present study is to explore knowledge, illness perceptions and stated practice behaviour in relation to gout in primary care. This is a mixed methods study among 32 general practitioners (GPs). The quantitative assessment included the Gout Knowledge Questionnaire (GKQ; range 0–10; better) and Brief Illness Perceptions Questionnaire(More)
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