Bart Pasternack

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Chloromethyl methyl ether (CMME) has been used extensively as a crosslinking agent for ion-exchange resins. Commercial grades of CMME are contaminated to the extent of 2-8% with bischloromethyl ether, an alkylating agent which has been shown to be a very potent lung carcinogen in animals. Reports by other investigators in this and other countries have(More)
The purpose of this case-control study was to identify susceptible subgroups, primarily based on pigmentary characteristics, at higher risk of developing melanoma when exposed to the sun. The study group, which was interviewed from 1979 to 1982, consisted of 289 consecutive patients with melanoma and 527 randomly selected controls without cancer. In(More)
only. 4. Briollais, L., et al., Genetic and epidemiological risk factors for a malignant melanoma-predisposing phenotype: the great number of nevi. Estimating the population attributable fraction for multiple risk factors using case-control data. Malignant melanoma risk factors by anatomic site: a case-control study and polychotomous logistic regression(More)
Background—Peroxisome proliferator-activated receptor ␣ (PPAR␣) regulates the expression of genes involved in lipid metabolism and inflammation, making it a candidate gene for atherosclerosis and ischemic heart disease (IHD). Methods and Results—We investigated the association between the leucine 162 to valine (L162V) polymorphism and a G to C transversion(More)
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