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Mobile information technology can help first responders assist patients more quickly, reliably, and safely, while focusing resources on those most in need. Yet the disaster setting complicates reliable networked computing. The WIISARD client-server architecture provides mobile IT support for medical response in disasters. Cached remote objects (CROs) are(More)
Cytoscape is one of the most popular open-source software tools for the visual exploration of biomedical networks composed of protein, gene, and other types of interactions. It offers researchers a versatile and interactive visualization interface for exploring complex biological interconnections supported by diverse annotation and experimental data,(More)
Modern genomic analysis often requires workflows incorporating multiple best-ofbreed tools. GenomeSpace is a web-based visual workbench that combines a selection of these tools with mechanisms that create data flows between them. One such tool is Cytoscape 3, a popular application that enables analysis and visualization of graph-oriented genomic networks.(More)
Complex biomedical analyses require the use of multiple software tools in concert and remain challenging for much of the biomedical research community. We introduce GenomeSpace (http://www.genomespace.org), a cloud-based, cooperative community resource that currently supports the streamlined interaction of 20 bioinformatics tools and data resources. To(More)
Networks are a powerful and flexible methodology for expressing biological knowledge for computation and communication. Network-encoded information can include systematic screens for molecular interactions, biological relationships curated from literature, and outputs from analysis of Big Data. NDEx, the Network Data Exchange (www.ndexbio.org), is an online(More)
Graphical Abstract Highlights d NDEx (www.ndexbio.org) is an online commons for biological networks d Users can upload, share, and distribute networks of many types, sizes, and formats d Developers can access NDEx via a web-based programming interface d NDEx promotes the publication of networks as dynamic, actionable data In Brief NDEx (www.ndexbio.org) is(More)
One of the key challenges to successful systems-of- systems integration using Web services technologies is how to address crosscutting architectural concerns such as policy management, governance, and authentication, while still maintaining the lightweight implementation and deployment flavor that distinguishes Web services from earlier attempts at(More)
The Network-extracted Ontology (NeXO) is a gene ontology inferred directly from large-scale molecular networks. While most ontologies are constructed through manual expert curation, NeXO uses a principled computational approach which integrates evidence from hundreds of thousands of individual gene and protein interactions to construct a global hierarchy of(More)
In this work we present CitiSense, a new kind RI ³FLWL]HQ LQIUDVWUXFWXUH´for the monitoring of pollution and environmental conditions that users are exposed to. By utilizing mobile phones and affordable, small sensors placed in the environment and carried by users, data about pollutants such as ozone and carbon monoxide is collected and used to provide(More)