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The influence of Fe status on cell-mediated immunity was studied in weanling mice fed on Fe-deficient (7 mg Fe/kg), Fe-sufficient (120 mg Fe/kg) and high-Fe (3000 or 5000 mg Fe/kg) diets for 7 weeks. The contact sensitivity (CS) response to dinitrofluorobenzene (DNFB), the in vivo delayed-type hypersensitivity (DTH) response to sheep erythrocytes (SRBC) and… (More)
SYNOPSIS. In the present paper, we are reviewing experimental evidence demonstrating that phagocytic cells, such as macrophages, may be used as a biomarker of immunotoxicity in wildlife studies. We will first present data obtained after exposure in vitro with selected chemicals showing the comparative sensitivity of phagocytic cells from different species.… (More)
The negative impacts of ergot contamination of grain on the health of humans and animals were first documented during the fifth century AD. Although ergotism is now rare in humans, cleaning contaminated grain concentrates ergot bodies in screenings which are used as livestock feed. Ergot is found worldwide, with even low concentrations of alkaloids in the… (More)
Strychnine poisoning was diagnosed in free-flying mallards (Anas platyrhynchos) and a ring-billed gull (Larus delawarensis) found dead on a pond in a zoo. The probable source of toxin was improperly applied strychnine-treated grain used for control of rodents on adjacent farm land. Ingesta of the birds contained 19.7-85.1 mg/kg of strychnine.
Normal cholinesterase activity in brain tissue was measured in various mammalian and avain species. The cholinesterase activity in the cerebrum of cattle, swine, sheep and horses was approximately 2-3 umoles/min/g of tissue in each instance. The whole brain cholinesterase activity of small feral mammals was approximately 2 to 5 fold greater than the… (More)