Barkha Gupta

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Formaldehyde resins are used to improve the wet strength of paper. During the sheet-forming process of paper manufacture, formaldehyde fumes are liberated. Twenty-two male subjects having such exposures in a paper mill and 27 unexposed subjects were clinically evaluated to determine the effect of low level formaldehyde exposure in a tropical country. The(More)
2,3,7,8-Tetrachlorodibenzo-p-dioxin (T'CDD) is reported to be one of the most toxic chemicals known. There has been variation in such reported toxic parameters as single oral LD50 dose, range of time interval from dosing until death, and toxic manifestations which an animal exhibits (1-4). It seemed most appropriate, therefore, that the mean values and(More)
Chlorodibenzo-p-dioxins, especially 2,3,7,8tetrachlorodibenzo-p-dioxin (TCDD), are among the most toxic compounds known. These compounds are found as contaminants of technical chlorophenols and their derivatives. A variety of pathologic condition have been associated with the injestion of products containing chlorodibenzo-p-dioxins. Toxic fat, the cause of(More)
Pulmonary function studies were conducted on 489 pesticide workers engaged in spraying operations on mango plantations. These workers were exposed to a variety of organochlorine and organophosphorus pesticides. A reference group consisting of 208 controls, belonging to the same socioeconomic stratum, was taken from the same area for purposes of comparison.(More)
Previous studies reported that subcutaneous administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) at a dose level of 3 ,pg/kg, in mice on days 6 through 15 of gestation produced pups with cleft palates and kidney anomalies (1). The C57B1/6 mouse was the most sensitive of the three strains tested to the TCDD-induced kidney effects, in that almost(More)
A polybrominated biphenyl fire retardant (Firemaster FF-1) was responsible for the widespread environmental contamination and animal losses in Michigan during 1973 and 1974. In Fischer 344/N rats orally given 30,100,300, and 1,000 mg/kg (5 days/week, 22 total doses) for 4.5 weeks and observed for 90 days after the start of treatment, the LD50 was determined(More)