Barbaros Ilıkkan

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Deficiency of the IL-1 receptor antagonist (DIRA) is a recently described rare autoinflammatory disease, caused by loss of function mutations in IL1RN leading to the unopposed activation of the IL-1 pathway. We describe a novel nonsense mutation in the IL1RN gene, associated with early intrauterine onset, death and multiorgan involvement in a prematurely(More)
Sum mary Aim: To investigate the neonatal morbidity and mortality results in PPROM. Material and Method: A review of 228 PPROM singleton pregnancies followed up in our clinic between 1996 and 2005 was performed. Results: The most common neonatal morbidities in PPROM cases are RDS, sepsis and IVH. The route of delivery does not affect NICU requirement,(More)
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