Barbara Wilhelm

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The Thought Translation Device (TTD) is a brain-computer interface based on the self-regulation of slow cortical potentials (SCPs) and enables completely paralyzed patients to communicate using their brain potentials. Here, an extended version of the TTD is presented that has an auditory and a combined visual and auditory feedback modality added to the(More)
Brain-computer interfaces (BCIs) enable humans or animals to communicate or control external devices without muscle activity using electric brain signals. The BCI used here is based on self-regulation of slow cortical potentials (SCPs), a skill that most people and paralyzed patients can acquire with training periods of several hours up to months. The(More)
Unresponsive patients with remaining cognitive abilities may be able to communicate with a brain-computer interface (BCI) such as the Thought Translation Device (TTD). Before initiating TTD learning, which may imply considerable effort, it is important to classify the patients' state of awareness and their remaining cognitive abilities. A tool for detection(More)
We summarize results from a series of related studies that aim to develop a motor-imagery-based brain-computer interface using a single recording session of electroencephalogram (EEG) or electrocorticogram (ECoG) signals for each subject. We apply the same experimental and analytical methods to 11 nonparalysed subjects (eight EEG, three ECoG), and to five(More)
OBJECTIVES Communication support for severely paralyzed patients with visual impairment is needed. Therefore, the feasibility of a brain-computer interface (BCI) using auditory stimuli alone, based on the self-regulation of slow cortical potentials (SCPs), was investigated. METHODS Auditory stimuli were used for task and feedback presentation in an SCP(More)
Self-regulation of slow cortical potentials (SCPs) has been successfully used to prevent epileptic seizures as well as to communicate with completely paralyzed patients. The thought translation device (TTD) is a brain-computer interface (BCI) that was developed for training and application of SCP self-regulation. To investigate the neurophysiological(More)
BACKGROUND SELEX is an iterative process in which highly diverse synthetic nucleic acid libraries are selected over many rounds to finally identify aptamers with desired properties. However, little is understood as how binders are enriched during the selection course. Next-generation sequencing offers the opportunity to open the black box and observe a(More)
The authors review the notes of 40 patients who underwent surgery for large sacral pressure sore over the last 10 years. In most cases a gluteus maximus flap with skin graft has been employed to cover sacral sore, as originally described by Ger in 1971. The results of this series are then compared with those published by other authors using different(More)
BACKGROUND Since January 2005, the situation of metabolic and obesity surgery in Germany has been constantly evaluated by the German Bariatric Surgery Registry (GBSR). Data registration is performed using an internet online database with prospective data collection. All registered data were analysed in cooperation with the Institute of Quality Assurance at(More)