Barbara Nowicki

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Imaging of the sacral plexus requires evaluation of both intradural and extradural components with cross-sectional techniques. Although CT is useful, individual extradural sacral nerves and the sacral plexus usually cannot be distinguished from adjacent structures. The higher contrast resolution provided by MR imaging allows the region of the sacral plexus(More)
STUDY DESIGN A cadaveric study was done to analyze the dimensional changes in the spinal canal and intervertebral foramen of the lumber spine with flexion and extension movements. OBJECTIVES To investigate the relationship between flexion and extension movements and morphologic changes in the spinal canal and the intervertebral foramen. SUMMARY OF(More)
PURPOSE To study the relationship of lumbar facet joint tropism to degeneration of the cartilage and subcortical bone in the facet joints and the effect of tropism in intervertebral disk degeneration. METHODS The orientation of 104 cadaveric lumbar facet joints with respect to sagittal plane was measured on CT scans, and the joints were classified as(More)
The hypothesis that the neural foramina in some patients are critically narrowed by axial compression of the spine has not been studied with direct imaging techniques. Frozen cadaveric motion segments of the lumbar spine (intervertebral disk and contiguous vertebrae) were imaged with computed tomography (CT). The segments were thawed and compressed in a(More)
PURPOSE To measure the effect of extension, flexion, lateral bending, and axial rotation loads applied to the spine on the anatomic relationship of the spinal nerves in the neural foramen to the ligamentum flavum and the intervertebral disk, anc to determine the effect of disk degeneration on the response to loading. METHODS Cadaveric lumbar motion(More)
PURPOSE To evaluate the MR appearance of the mandibular canal and its contents. METHODS Cadaveric mandibles were imaged at 1.5 T and 3 T, then sectioned with a cryomicrotome. The size, shape, signal intensity, and pattern of structures in the mandibular canal were identified on MR images by comparing them with corresponding anatomic sections. RESULTS(More)
[Carbonyl-(11)C]WAY-100635 ([(11)C]WAY) is an established radioligand for the study of brain serotonin(1A) (5-HT(1A)) receptors in living animals and humans with positron emission tomography (PET). There is a recognised need to develop halogenated ligands for 5-HT(1A) receptors, either for labelling with longer-lived fluorine-18 for more widespread(More)
Axial and parasagittal computed tomographic (CT) scans and magnetic resonance (MR) images and exactly corresponding sections obtained with the freezing microtome in 18 human cadavers were examined to characterize the radiologic appearance of the lumbar neural forminal ligaments, which have been thought to contribute to nerve root compression. In the CT(More)
We evaluated the effects of various schedules of peripheral blood stem cell (PBSC) reinfusion, granulocyte colony-stimulating factor (G-CSF) priming, and CD34+ enrichment on hematopoietic recovery in 88 patients with advanced breast cancer treated with high-dose chemotherapy, consisting of cisplatin 250 mg/m2, etoposide 60 mg/kg, and cyclophosphamide 100(More)
BACKGROUND Autologous hematopoietic stem cell transplantation (HSCT) of gene-modified cells is an alternative to enzyme replacement therapy (ERT) and allogeneic HSCT that has shown clinical benefit for adenosine deaminase-deficient (ADA-deficient) SCID when combined with reduced intensity conditioning (RIC) and ERT cessation. Clinical safety and therapeutic(More)