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Therapeutic human papillomavirus vaccines: current clinical trials and future directions

• Chien Fu Hung, Barbara Ma, Archana Monie, Shaw Wei Tsen, T C Wu
• 2008

Development of a DNA vaccine targeting Merkel cell polyomavirus.

• Qi Zeng, Bianca P Gomez, +5 authors Chien-fu Hung
• Vaccine
• 2012

Merkel cell carcinoma (MCC) is a rare but devastating skin disease that is increasing in incidence within the United States. The poor prognosis of MCC patients and limited understanding of MCC… (More)

Immunotherapy for Cervical Cancer

• Jun-Han Su, Anjui Wu, +4 authors Dr T.-C. Wu
• BioDrugs
• 2010

The high-risk types of human papillomavirus (HPV) have been found to be associated with most cervical cancers and play an essential role in the pathogenesis of the disease. Despite recent advances in… (More)

Emerging human papillomavirus vaccines.

• Barbara Ma, Bharat Maraj, +5 authors T. -C Wu
• Expert opinion on emerging drugs
• 2012

INTRODUCTION Identification of human papillomavirus (HPV) as the etiologic factor of cervical, anogenital, and a subset of head and neck cancers has stimulated the development of preventive and… (More)

HPV and Therapeutic Vaccines : Where are We in 2010 ?

• Barbara Ma, Yijie Xu, Chien-fu Hung, T. K. Wu
• 2010

The discovery of human papillomavirus (HPV) as a necessary etiological factor for cervical cancer has spurred the development of preventive and therapeutic HPV vaccines for the control of… (More)

Rigorous Development does not Ensure that Guidelines are Acceptable to a Panel of Knowledgeable Providers

• Mshs Teryl K. Nuckols MD, PhD Yee-Wei Lim MD, +7 authors Mph Steven Asch MD
• Journal of General Internal Medicine
• 2007

Rigorous guideline development methods are designed to produce recommendations that are relevant to common clinical situations and consistent with evidence and expert understanding, thereby promoting… (More)

LAH4 enhances CD8+ T cell immunity of protein/peptide-based vaccines.

• Tong Zhang, Tae Heung Kang, Barbara Ma, Yijie Xu, Chien-fu Hung, T. -C Wu
• Vaccine
• 2012

It is now clear that CD8+ T cells are crucial for therapeutic immunity against chronic viral infections and/or tumors. We reason that a strategy capable of improving CD8+ T cell activation would… (More)

Targeted Coating With Antigenic Peptide Renders Tumor Cells Susceptible to CD8+ T Cell-mediated Killing.

• Tae Heung Kang, Barbara Ma, Connie Wang, T C Wu, Chien Fu Hung
• 2013

The potency of immunotherapies targeting endogenous tumor antigens is hindered by immune tolerance. We created a therapeutic agent comprised of a tumor-homing module fused to a functional domain… (More)

Current status of human papillomavirus vaccines.

• Barbara Ma, Richard B S Roden, T C Wu
• Journal of the Formosan Medical Association…
• 2010

Treatment with cyclooxygenase-2 inhibitors enables repeated administration of vaccinia virus for control of ovarian cancer.

• Chih-Long Chang, Barbara Ma, Xiaowu Pang, T. -C Wu, Chien-fu Hung
• Molecular therapy : the journal of the American…
• 2009

Metastatic ovarian cancer is the leading cause of death among women with gynecologic malignancies in the United States. The lack of effective treatment for patients with advanced ovarian cancer… (More)

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