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A representation and interpretation of the area under a receiver operating characteristic (ROC) curve obtained by the "rating" method, or by mathematical predictions based on patient characteristics, is presented. It is shown that in such a setting the area represents the probability that a randomly chosen diseased subject is (correctly) rated or ranked(More)
Receiver operating characteristic (ROC) curves are used to describe and compare the performance of diagnostic technology and diagnostic algorithms. This paper refines the statistical comparison of the areas under two ROC curves derived from the same set of patients by taking into account the correlation between the areas that is induced by the paired nature(More)
Correlates of physicians' liking for their patients were examined among 17 internists at a health maintenance organization and 530 of their patients 70 years of age and older. Analyses were conducted for the entire sample as well as for individual physicians, whose results were combined by meta-analysis. Both kinds of analysis showed that patients were more(More)
D IAGNOSIS AND RECOGNITION of disease using diagnostic imaging has undergone significant change and development in the past 25 years. This article focuses on 3 major areas of imaging: new techniques, image-guided therapy, and bioinformatics, each of which reflects the dramatic progress in this field. Development of magnetic resonance imaging (MRI), computed(More)
This paper estimates the value of medical research, using cardiovascular disease as a case study. We highlight two roles of medical research: the new therapies it leads to; the information that is provided to consumers, allowing for health-improving behavioral changes. We estimate the return to new medical treatments at about 4 to 1 and the return to health(More)
An online survey of deans/directors of 266 baccalaureate and higher nursing programs in the U.S. was developed by informatics expert nurses. Participants (1) identified nursing informatics (NI) competencies and knowledge of undergraduate and/or graduate students in their nursing programs; (2) determined faculty preparedness to teach NI and to use(More)
BACKGROUND Some have the opinion that patients cared for in Veterans Health Administration (VHA) hospitals receive care of poorer quality than those cared for in non-VHA institutions. To assess the quality of care in VHA hospitals, we compared the outcome of acute myocardial infarction among patients in VHA and non-VHA institutions while controlling for(More)
PURPOSE To compare the accuracies of computed tomography (CT), magnetic resonance (MR) imaging, and bone scintigraphy in staging disease in patients with neuroblastoma. MATERIALS AND METHODS Ninety-six children with newly diagnosed neuroblastoma were enrolled in a multicenter prospective cohort study. CT, MR, and bone scintigraphy were used to evaluate(More)
This exploratory study examined the extent to which factors beyond characteristics of the patient, such as discharging hospital attributes and State factors, contributed to variations in post-acute services use (PASU) in a cohort of elderly Medicare patients following acute myocardial infarction (AMI). Thirty-seven percent of this cohort received PAS within(More)
Assignment Potential (AP) is a performance measure of a diagnostic test, characterizing the chance that, as a consequence of performing the test, the probability of disease will exceed a decision threshold, thereby permitting a management action to be taken. Another performance measure, Assignment Strength (AS) characterizes the average extent to which a(More)