Barbara E. Goodman

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We investigated effects of acute hyperoxia on solute transport from air space to vascular space in isolated rat lungs. Air spaces were filled with Krebs-Ringer bicarbonate solution containing fluorescein isothiocyanate-labeled dextran (FD-20; mol wt 20,000) and either 22Na+ and [14C]sucrose, or D-[14C]glucose and L-[3H]glucose. Apparent permeability-surface(More)
Ion channels are essential for the basic physiological function of excitable cells such as nerve, skeletal, cardiac, and smooth muscle cells. Mutations in genes that encode ion channels have been identified to cause various diseases and disorders known as channelopathies. An understanding of how individual ion channels are involved in the activation of(More)
Channels active in the excitability of nerves and skeletal muscles across the neuromuscular junction: basic function and pathophysiology Goodman BE. Channels active in the excitability of nerves and skeletal muscles across the neuromuscular junction: basic function and pathophysiology. channels are essential for the basic physiological function of excitable(More)
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