Barbara C. Potts

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In this study, we used a procedure called selective/divided rotation to investigate the role of dimensions in the perception of color. Ss performed either selective-attention or divided-attention tasks to paired dimensions created from each of 3 orientations of axes in color space: 0 degree, 22.5 degrees, and 45 degrees. We evaluated a Euclidean hypothesis,(More)
In six experiments using the speeded classification paradigm, we provide evidence that the ostensibly "separable" dimensions of size and orientation can produce patterns of either separability or asymmetric configurality, depending on the spatial arrangement of the stimuli. In all experiments, subjects classified large or small circles containing a single(More)
The salinosporamides are potent proteasome inhibitors among which the parent marine-derived natural product salinosporamide A (marizomib; NPI-0052; 1) is currently in clinical trials for the treatment of various cancers. Methods to generate this class of compounds include fermentation and natural products chemistry, precursor-directed biosynthesis,(More)
In vitro metabolism of AG7088 [trans-(4S,2'R,5'S,3"'S)-4-[2'-4-(4-fluorobenzyl)-6'-methyl-5'-[(5"-methylisoxazole-3"-carbonylamino]-4-oxoheptanoylamino]-5-(2"'-oxopyrrolidin-3-"'-yl)pent-2-enoic acid ethyl ester] was studied in liver microsomes isolated from mice, rats, rabbits, dogs, monkeys, and humans. The structures of the metabolites were characterized(More)
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