Barbara Brokate

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The effect of long-term heavy alcohol consumption on brain functions is still under debate. The authors investigated a sample of 17 Korsakoff amnesics, 23 alcoholics without Korsakoff's syndrome, and 21 controls with peripheral nerve diseases, matched for intelligence and education. Executive functions were examined for word fluency, the modified Wisconsin(More)
Chronic alcohol abuse leads to cognitive deficits. The authors investigated whether a systematic increase of interference in a 2-back working memory paradigm would lead to cognitive deficits in alcoholic participants and compared their performance in such a task with that in an alternate-response task. Twenty-four nonamnesic and nondemented alcohol abuse(More)
Bechara (2003) describes a model for disturbances in executive functions related to addiction. This model involves deficits in decision-making and in suppressing pre-potent representations or response patterns. We tested this model in 29 individuals with long-term heavy alcohol dependency and compared their performance with that of 20 control subjects. Only(More)
To compare the neuropsychological deficits of primary progressive multiple sclerosis with those of relapsing–remitting and secondary progressive multiple sclerosis. Sixtyfive patients with different clinical courses of MS were neuropsychologically tested for language, attention, memory and executive functions. Discriminant analysis was used to predict the(More)
Substance dependency has been related to an impairment in executive functions and to a dysfunction of the frontal cortex. In this study we developed two experimental tasks, which are physically identical, to analyze whether substance-dependent individuals are impaired in shifting response patterns (stimulus response links) or preferences (stimulus outcome(More)
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