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Chloroquine inhibits cell growth and induces cell death in A549 lung cancer cells.
Effective removal of heavy metal ions Cd2+, Zn2+, Pb2+, Cu2+ from aqueous solution by polymer-modified magnetic nanoparticles.
A new microRNA signal pathway regulated by long noncoding RNA TGFB2-OT1 in autophagy and inflammation of vascular endothelial cells
This data indicates that NUPR1 and TIA1 may control the level of TGFB2-OT1, and TGF b2OT1 bound to MIR3960, MIR4488 and MIR4459, which targeted CERS1, NAT8L, and LARP1, respectively, the key proteins involved in autophagy and inflammation.
An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E-/- mice
Results showed that oxLDL inhibited the activity of mTOR and increased the protein level of autophagy-related 13 (ATG13) and its dephosphorylation, thus inducingAutophagy in human umbilical vein endothelial cells (HUVECs).
Identification of a novel MTOR activator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells
3BDO is provided as a new activator of MTOR, and the role of the lncRNA in autophagy is highlighted, which is involved in cancer and cardiovascular and neurological diseases.
Synthesis and structure-activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives as potential agents against A549 lung cancer cells.
Synthesis and structure-activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide derivatives as potential agents against A549 lung cancer cells.
Efficient removal of cationic dyes from aqueous solution by polymer-modified magnetic nanoparticles
A novel water treatment magnetic nanomaterial for removal of anionic and cationic dyes under severe condition