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BACKGROUND AND OBJECTIVE Th17 cells are important T helper cells, which are characterized by their production of IL-17. Th17 cells play an important role in host defense against microbial infections, autoimmune diseases and cancer. The aim of this study is to investigate the percentage of Th17 in peripheral blood lymphocyte and the level of IL-17 in serum(More)
Four meso-tetraphenylporphyrin derivatives bearing either triphenylphosphonium ion-(P1 and P2) or triethylammonium ion-(P3 and P4) terminated alkoxy group at either para-(P1 and P3) or meta-(P2 and P4) position of one meso-phenyl group were designed and synthesized. P1-P4 show similar absorption and fluorescence emission spectra and (1)O(2) quantum yields.(More)
[Ru(II)(bpy)(2)(dppn)](2+) (bpy = 2,2'-bipyridine, dppn = 4,5,9,16-tetraazadibenzo[a,c]naphthacene) was found to be able to photoinactivate Gram-negative Escherichia coli efficiently, showing the potential of transition-metal complexes as photosensitizers in the field of photodynamic antimicrobial chemotherapy (PACT).
Hypocrellin A (HA), an efficient phototherapeutic agent, can chelate with lanthanum ion to form a 1:1 complex, which exhibits enhanced 1O2 generation quantum yield, a red-shifted absorption window, greatly improved water solubility, a much lengthened triplet excited state lifetime, and an increased affinity to DNA with respect to HA. These effects in turn(More)
An amphiphilic barbituric acid derivative was found to form stable monolayers showing a clear phase transition at the air/water interface. It is interesting to find that the deposited Langmuir-Blodgett (LB) films of the compound showed circular dichroism (CD) although the molecule itself was achiral. AFM measurements on the transferred one-layer LB film(More)
Many plant receptor kinases transduce signals through receptor-like cytoplasmic kinases (RLCKs); however, the molecular mechanisms that create an effective on-off switch are unknown. The receptor kinase BR INSENSITIVE1 (BRI1) transduces brassinosteroid (BR) signal by phosphorylating members of the BR-signaling kinase (BSK) family of RLCKs, which contain a(More)
To track nuclear dynamic processes by fluorescence imaging, nuclear stains should be highly fluorescent, resistant to photobleaching, and inert to nuclear processes. The nuclear stains of the Hoechst family, such as Hoechst 34580, show bright fluorescence only on groove binding to DNA, and therefore may interfere with visualization of nuclear dynamic(More)
[Cu(TMPA)Cl]Cl (1) and [Cu(Cl-TMPA)Cl2] (2) exhibited efficient photocatalytic H2 evolution with a TON of 6108 and 10014 (6 h), respectively, in CH3CN/H2O solution (9 : 1, v/v) containing an Ir complex as the photosensitizer and triethylamine as the sacrificial reductant, representing the first example of photocatalytic Cu complex-based water reduction(More)
Transition metal complexes with dual functions of DNA photobinding via coordination and DNA photocleavage via(1)O2 may present potent antitumor activities with high selectivity and a wide anticancer spectrum. We herein report such a complex, [(η(6)-p-cymene)Ru(dpb)(py)](2+) (dpb = 2,3-bis(2-pyridyl)benzoquinoxaline, py = pyridine, 1). The highly delocalized(More)