Share This Author
Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NFκB and ERK pathways in Raw 264.7 cells
- Haijian Sun, Weiwei Cai, Liying Qiu
- Biology, MedicineBMC Complementary and Alternative Medicine
- 20 February 2017
It was seen that vaccaria hypaphorine counteracted inflammation via inhibition of ERK or/and NFκB signaling pathways and can be served as an anti-inflammatory candidate.
Endothelial dysfunction and cardiometabolic diseases: Role of long non-coding RNAs.
T-Cell Autophagy Deficiency Increases Mortality and Suppresses Immune Responses after Sepsis
It is indicated that sepsis led to down-regulation of autophagy in T lymphocytes, which may result in enhanced apoptosis induction and decreased survival in sepsi, and Autophagy may play a protective role against sepsIS-induced T lymphocyte apoptosis and immunosuppression.
Preparation, characterization and wound healing effect of vaccarin-chitosan nanoparticles.
Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway
Vaccarin hastens wound healing by promoting angiogenesis via activation of MAPK/ERK and PI3K/AKT signaling pathways in vivo 1
The present study was the first to demonstrate that vaccarin is able to induce angiogenesis and accelerate wound healing in vivo by increasing expressions of p-Akt, p-Erk and p-bFGFR, mediated by MAPK/ERK and PI3K/AKT signaling pathways.
Vaccarin protects human microvascular endothelial cells from apoptosis via attenuation of HDAC1 and oxidative stress
Protective Effects and Mechanisms of Vaccarin on Vascular Endothelial Dysfunction in Diabetic Angiopathy
- Fei Xu, Yixiao Liu, Liying Qiu
- Biology, MedicineInternational journal of molecular sciences
- 1 September 2019
It is found that VAC attenuated increased blood glucose, increased glucose and insulin tolerance, relieved the disorder of lipid metabolism and oxidative stress, and improved endothelium-dependent vasorelaxation in STZ/HFD-induced T2DM mice.
1,25(OH)2D3 mitigate cancer-related fatigue in tumor-bearing mice: Integrating network pharmacological analysis.
Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo
VNE could effectively depress the expressions of proinflammatory cytokines, including IL-1β, IL-6, TNF-α, and COX-2, and demonstrated that VNE may be a promising therapeutic agent against the inflammation and diseases caused by T. spiralis infection.