Bandi Srinivasulu

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A new strain of Streptomyces fradiae, isolated and identified in our laboratory, was found to be a potential producer of protease enzyme. An enzyme yield of 285 P.U./ml. was obtained prior to optimization in a synthetic medium containing potato starch, potassium nitrate and trace salts by shake flask method. The carbon and nitrogen compounds play prominent(More)
The purpose of this investigation was to study the effect ofStreptomyces marinensis NUV-5 cells immobilized in calcium alginate for the production of neomycin. The effect of various parameters, such as the effect of alginate concentration (1%, 2%, 3%, 4%, and 5% wt/vol), the effect of cation (caCl2, BaCl2, and SrCl2), the concentration of cation (0.01M,(More)
Cephalosporium acremonium ATCC 48272 cells were immobilized on various adsorbents and in various entrapment matrices. The influence of the incubation period, the best immobilization technique and the optimum concentrations of the selected matrices were investigated. From the results of the repeated batch fermentation in shake flasks, a good level of(More)
About 359 actinomycetes were isolated from 8 different natural substrates collected from different parts of Andhra Pradesh. The isolates were screened on the basis of their inhibitory effect against test organisms. Finally one potent antibiotic producer was chosen having broad-spectrum activity against Gram-positive and Gram-negative bacteria and it was(More)
Treatment of spore suspension of Cephalosporium acremonium ATCC 48272 with UV rays and N-methyl-N-nitro-N-nitrosoguanidine (NTG) induced mutants capable of producing higher yields of cephalosporin C. Antibiotic yield was improved from 630 micrograms/ml to 1995 micrograms/ml of the broth resulting in a high yielding mutant.
The cysteine-rich peptide hepcidin is an antimicrobial peptide and iron transport regulator that has been found in vertebrates including birds, fish and mammals. To elucidate the structure and biological function of fish hepcidin, which is difficult to produce synthetically, we have cloned several plasmid constructs encoding hepcidin from Japanese flounder,(More)
A new strain of Bacillus sp., Bacillus PE-11 isolated and identified in our laboratory was found to be a potential producer of alkaline proteinase. The production of proteinase was studied in thirteen different reported media to select the optimal production medium. In all the reported media, the medium XII of composition: glucose, 0.2%; peptone, 1.5%; salt(More)
Stirred tank, fluidized bed, and airlift reactors produced similar neomycin activity with immobilized cells. Packed bed reactor clearly under performed, probably because of insufficient aeration or mixing. Neomycin production using immobilized cells in fermentors requires good mixing and aeration.
Pycnidia in groups, scattered forming crusts at maturity, stroma cortical to subcoI tical, rupturing irregularly or at apex at maturity, 140--200 × 55---130 #. Conidiophores short, simple, hyaline 1 0 1 8 × 3--4 #, from tip are produced conidia which are hyaline, oblong to ellipsoid, one celled, 16--21 × 9--14 #, released at maturi ty in the central cavity.(More)
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