Balu Mahendran

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BACKGROUND Plasma Haemoglobin A1c (HbA1c) reflects ambient mean glycaemia over a 2-3 months period. Reports indicate that patients, with and without diabetes, with an elevated HbA1c have an increased risk of adverse outcome following surgical intervention. Our aim was to determine whether elevated plasma HbA1c level was associated with increased(More)
OBJECTIVES The aim of this study is to assess the influence of subintimal angioplasty (SIA) on lower limb amputation rate and level in critically ischaemic limbs. METHODS Between January 1989 and March 2004, 1268 patients were admitted for treatment of lower limb critical ischaemia. Eight hundred and twenty-nine patients underwent revascularisation(More)
INTRODUCTION Alteration in the expression of extracellular matrix metalloproteinase inducer (EMMPRIN), matrix metalloproteinase-2 (MMP-2), tissue inhibitors of matrix metalloproteinases (TIMP-2) and platelet derived growth factor (PDGF-AA) may contribute to poor healing in venous leg ulcers. AIM The aim of this study is to determine the expression of(More)
Back ground: Alcoholic cirrhosis is a condition of irreversible liver disease due to the chronic inflammatory and toxic effects of ethanol on the liver. Acute alcoholic hepatitis occurs in habitual drinkers, often a period of increased alcohol intake. Although, the clinical features may mimic acute viral hepatitis. Progression of liver fibrosis to cirrhosis(More)
Sialic acid-rich glycoprotein is found mainly in cell membranes, and elevated levels may indicate excessive cell membrane damage, but more specifically for cells of vascular tissue. Serum total Sialic acid is a marker of the acute phase response. Elevated levels have also been associated with cardiovascular disease especially in Type 2 diabetic subjects.(More)
Serum total homocysteine (tHcy) concentration is associated with increased risk factor for coronary heart diseases (CHD). The relation between type2 diabetes mellitus compared to the non diabetics is not clear. The current study represents an association between tHcy and cardiovascular disease is stronger in diabetics than in non-diabetic subjects.(More)
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