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—A key feature of Information-Centric Networking architectures is universal caching where anyone can cache any content and users can obtain the content from anywhere as long as the content itself is intact. This powerful feature benefits the content providers, the Internet service providers (ISPs) as well as end users since the requested content can be(More)
The isothiocyanate analog (IBI) of tolazoline produced contraction of the rat aortic strip, with an ED50 value of 1.63 x 10(-5) M. The maximum contraction of the analog was nearly equal to that of tolazoline or phenylephrine. At 27 degrees C the tissue reactivity of phenylephrine and IBI was similar. When compared at equiactive concentrations, the total(More)
Tolazoline and two 4'-substituted benzyl analogues, 2-(4'-aminobenzyl) imidazoline (ABI) and 2-(4'-isothiocyanatobenzyl)imidazoline (IBI) were synthesized and evaluated for adrenoceptor activity in human platelets (alpha 2) and rat aorta (alpha 1), respectively. IBI was prepared as an affinity label for alpha-adrenoceptors and compared with(More)
Content-Centric Networking (CCN) is a promising candidate for the future Internet architecture. Its pivot is to change the host-centric model of the current Internet to a content-centric model. Under the new model, anyone can cache contents and serve them to anyone else. Thus, user latency, redundant traffic and server load are all reduced. Although CCN is(More)
Seven analogues of medetomidine and naphazoline were synthesized and evaluated for their alpha 1 (aorta) and alpha 2 (platelet) activities. The analogues were composed of 2- and 4-substituted imidazoles and imidazolines attached through a methylene bridge to either the 1- or 2-naphthalene ring system. In general the 1-naphthalene analogues were the most(More)
Oxidative damage to crucial biomolecules due to excess generation of reactive oxygen species has been implicated as a major cause of organ damage and hence compounds capable of negating such damage have potential benefits. Using hydrogen peroxide (H2O2) as a model pro-oxidant to induce oxidative stress, we have examined the ability of natural food(More)
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