Balaji Ganeshan

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PURPOSE To determine if computed tomographic (CT) texture features of primary colorectal cancer are related to 5-year overall survival rate. MATERIALS AND METHODS Institutional review board waiver was obtained for this retrospective analysis. Texture features of the entire primary tumor were assessed with contrast material-enhanced staging CT studies(More)
BACKGROUND Tumor spatial heterogeneity is an important prognostic factor, which may be reflected in medical images METHODS Image texture analysis is an approach of quantifying heterogeneity that may not be appreciated by the naked eye. Different methods can be applied including statistical-, model-, and transform-based methods. RESULTS Early evidence(More)
PURPOSE To assess changes in tumor computed tomographic (CT) texture after two cycles of treatment with tyrosine kinase inhibitors (TKIs) and to determine if tumor texture correlates with measured time to progression in patients with metastatic renal cell cancer who received TKIs. MATERIALS AND METHODS A waiver of institutional review board approval was(More)
To establish the potential for tumour heterogeneity in non-small cell lung cancer (NSCLC) as assessed by CT texture analysis (CTTA) to provide an independent marker of survival for patients with NSCLC. Tumour heterogeneity was assessed by CTTA of unenhanced images of primary pulmonary lesions from 54 patients undergoing 18F-fluorodeoxyglucose (FDG) PET-CT(More)
AIM To undertake a pilot study assessing whether tumour heterogeneity evaluated using computed tomography texture analysis (CTTA) has the potential to provide a marker of tumour aggression and prognosis in oesophageal cancer. MATERIALS AND METHODS In 21 patients, unenhanced CT images of the primary oesophageal lesion obtained using positron-emission(More)
PURPOSE To assess the utility of texture analysis of liver computed tomographic (CT) images by determining the effect of acquisition parameters on texture and by comparing the abilities of texture analysis and hepatic perfusion CT to help predict survival for patients with colorectal cancer. MATERIALS AND METHODS The study comprised a phantom test and a(More)
Analysis of texture within tumours on computed tomography (CT) is emerging as a potentially useful tool in assessing prognosis and treatment response for patients with cancer. This article illustrates the image and histological features that correlate with CT texture parameters obtained from tumours using the filtration-histogram approach, which comprises(More)
PURPOSE We prospectively examined the role of tumor textural heterogeneity on positron emission tomography/computed tomography (PET/CT) in predicting survival compared with other clinical and imaging parameters in patients with non-small cell lung cancer (NSCLC). EXPERIMENTAL DESIGN The feasibility study consisted of 56 assessed consecutive patients with(More)
PURPOSE To determine the association between tumor heterogeneity, morphologic tumor response, and overall survival in primary esophageal cancer treated with chemotherapy and radiation therapy (CRT). MATERIALS AND METHODS After an institutional review board waiver was obtained, contrast material-enhanced computed tomographic (CT) studies in 36 patients(More)
PURPOSE To evaluate whether changes in magnetic resonance (MR) imaging heterogeneity may aid assessment for pathologic complete response (pCR) to neoadjuvant chemotherapy (NACT) in primary breast cancer and to compare pCR with standard Response Evaluation Criteria in Solid Tumors response. MATERIALS AND METHODS Institutional review board approval, with(More)