Balázs Lukáts

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The nucleus accumbens, a key structure of the limbic circuitry, is involved in the regulation of motivated behaviors. The accumbens performs its roles via interconnections with brain areas where glucose-monitoring neurons have been localized. To search for such integrative chemosensory cells here, extracellular single neuron activity was recorded in the(More)
Introduction The ventromedial hypothalamic nucleus (VMH), the nucleus accumbens (NAcc) and the mediodorsal and ventrolateral prefrontal (orbitofrontal) cortices (mdPFC and OBF, respectively), key structures of the forebrain limbic circuitry, are known to play important roles in various mechanisms of the homeostatic regulation In previous studies, special(More)
The ventromedial hypothalamic nucleus (VMH) is a central site of action of interleukin-1beta (IL-1beta) induced feeding disturbances. This study was designed to elucidate taste-related perceptual and motivational processes potentially contributing to the anorexia and adipsia seen after bilateral IL-1beta microinjection into the VMH. A saccharin conditioned(More)
The present study investigates the effects of direct administration of interleukin-1beta (IL-1beta) into the nucleus accumbens (NAcc) on homeostatic regulation. Short- and long-term food intakes (FI), water intakes (WI) and body temperature (BT) were measured before and after bilateral microinjection of IL-1beta (with or without paracetamol pretreatment)(More)
Macaque monkeys have a highly evolved visual system comparable to that of humans. One of the important visual functions is performing discriminations among biologically significant objects such as food or heterosexual partners. In the present study, we examined whether rhesus monkeys could categorize two-dimensional images related to food or gender using a(More)
BACKGROUND Peritubular endothelium plays a key role in the development and progression of diabetic and nondiabetic chronic kidney disease. Renal injury in disorders of glucose metabolism may appear as early as in the stage of impaired glucose tolerance (IGT) and is accelerated by hypertension. The aim of our study was to investigate renal histology in rats(More)
The orbitofrontal cortex (OBF) is known to play important roles in various regulatory processes. Our preliminary behavioral studies showed homeostatic alterations after orbitofrontal cortical microinjection of interleukin-1beta (IL-1beta) in the rat. To elucidate whether the above alterations were due to direct neuronal action of the cytokine, extracellular(More)
AIM Anorexia nervosa is a complex psychiatric disorder posing a rapidly increasing burden on modern societies. Our purpose was to clarify perceptual-motivational aspects of gustatory disturbances in the disease. METHODS A taste reactivity test, with the use of all five primary qualities in two concentrations, was performed in restrictive-type anorexic(More)