Backhoff David

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Some cases of peripheral neuropathy associated with benign IgM monoclonal gammopathy, or Waldenström's macroglobulinemia, are probably of autoimmune origin; in some cases, anti-IgM serum reacts with the myelin sheaths of peripheral nerves. However, mechanisms may differ in other cases. In one case of neuropathy with macroglobulinemia, we found deposits of(More)
OBJECTIVE To assess outcomes for patients treated with interferon beta-1b immediately after clinically isolated syndrome (CIS) or after a short delay. METHODS Participants in BENEFIT (Betaferon/Betaseron in Newly Emerging MS for Initial Treatment) were randomly assigned to receive interferon beta-1b (early treatment) or placebo (delayed treatment). After(More)
A 65 year-old man presented with a 8 months history of ataxia and weakness of the lower limbs. Acroparesthesias had been present for ten years in all four limbs. Serum protein electrophoresis showed a monoclonal IgM kappa spike. Bone marrow showed no increase in plasma cells. Motor conduction velocities were reduced. A biopsy from the right superficial(More)
Complement fixation (CF) and haemagglutination (HAP) with M. pneumoniae antigen have proved valuable methods for the etiological diagnosis of acute respiratory infections. Both methods are sensitive and specific, provided purified antigens are used, of the Kenny and Grayston lipid antigen type for CF and the antigen treated by ultrasound and purified by(More)
Accessory atrioventricular pathways (AP) and dual AV nodal physiology are common substrates for paroxysmal supraventricular tachycardias (SVT) in children and adolescents. Definitive treatment can be achieved by catheter ablation with either radiofrequency (RF) or cryoenergy. Aim of this study was to assess effectiveness and safety of RFand cryoenergy(More)
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